The human brain during rest - imaging, dynamics, patterns
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TALK
Prof. Henning U. Voss (Weill Cornell Medical College, New York), 5 July 2010, 10 a.m., HF136
The human brain during rest - imaging, dynamics, patterns
During rest, or more specifically, when subjects are instructed to think of nothing in particular, functional MRI of the human brain shows low frequency oscillations over the entire brain.
Spatiotemporal analysis of the associated blood-oxygen-level-dependent (BOLD) signals reveals spatial patterns of correlated activity that correspond to known functionally connected regions of the brain. Furthermore, there seem to be dependencies between low frequency BOLD signals and power fluctuations in EEG signals.
These findings are reviewed and alterations of these signals in subjects with severe brain injury are presented.
Further, it is discussed how advanced analysis and modeling of the spatiotemporal dynamics of the BOLD signal could contribute to a better understanding of these low frequency BOLD oscillations in the resting state.